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PUBLICATIONS
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Hypothesis-derive research
Hypothesis-driven research1. Hochberg Z. Treatment of familial dysautonomia with bethanecol. J Pediatr 89;862‑3, 1976.2. Hochberg Z, Kahana L, Spiendel A, Diengott D. Plasma renin activity in familial dysautonomia: Unresponsiveness to a beta‑adrenergic blocker. Pediatrics 58;618‑20, 1976. 3. Hochberg Z. Abnormal excretion of phenolic acids in rheumatic chorea. Isr J Med Sci. 15;223‑6, 1978.4. Hochberg Z, Dickerman Z, Kaufman H, Laron Z. Evaluation of the renin aldosterone system during hypo‑ and hyperglycemia in children and adolescence. Hormone Res 12;16‑21, 1980.5. Hochberg Z, Hardoff D. Quantitative assessmant of nutritional rickets by urinary phosphorus excretion. Acta Paediatr Scand 70;579‑80, 1981.6. Richman RA, Post EM, Nottman DD, Hochberg Z, Moses AM. Simplifying the diagnosis of diabetes insipidus in children. Amer J Dis Child 135;839‑41, 1981.7. Hochberg Z, Richman RA. Unstable osmoreceptors and deficient thirst in hypothalamic hypopituitarism. Hormone Res 14;215‑23, 1981.8. Hochberg Z, Weiss J, Richman RA. Inhibin like activity in rabbit placentae. Plecenta 2;259‑64, 1981.9. Richman RA, Weiss J, Hochberg Z, Florini J. Regulation of growth hormone release: evidence against negative feedback in rat pituitary cells. Endocrinol 108;2287‑92, 1981.10. Hochberg Z, Perlman R, Benderli A, Brandes JM. The effect of glucose, 2‑deoxy‑d‑glucose and insulin on estradiol secretion by cultures human trophoblast. Biochem Biophys Res Commun 108;102‑9, 1982. 11. Hochberg Z, Moses AM, Miller M, Benderly A, Richman RA. Altered osmotic threshold for vasopressin release and impaired thirst sensation: additional abnormalities in Kallman's syndrom. J Clin Endocrinol Metab 55;779‑782, 198212. Feldman D, Chen T, Cone C, Hirst M, Shani, Benderly A, Hochberg Z. Vitamin‑D resistant rickets with alopecia: cultured skin fibroblasts exhibit defective cytoplasmic receptors and unresponsiveness to 1,25(OH)2D3. J Clin Endocrinol Metab 55;1020‑2, 1982.13. Abend M, Hochberg Z, Borochowitz Z, Berger A. Low dose continuous intravenous insulin infusion on the first day of life in a ketoacidotic newborn. Europ J Pediatr 138;345‑6, 1982.14. Hochberg Z, Benderly A. Normal osmotic threshold for vasopressin release in the hyponatremia of hypothyroidism. Hormone Res 17;128‑33, 1983.15. Hochberg Z, Amit T, Youdim MBH, Bar‑Maor Y. Prolactin binding by testes of unilaterally cryptorchid rats: The effect of hCG, testosterone prolactin and orchiopexy. Acta Endocrinol 102;144‑9, 1983.16. Hochberg Z, Kutten A, Hertz P, Tatcher M, Kedar A, Benderly A. The effect of single dose radiation on cell survival and growth hormone secretion by rat anterior pituitary cells. Radiat Res 94;508‑12, 1983.17. GreiffZ, Benderly A, Levy J, Hochberg Z. Growth enhancement induced by prolonged L-dopa administration in rats. Biochem Med 30;53‑8, 1983.18. Hochberg Z, Perlman R, Brandes JM, Benderly A. Insulin regulates placental lactogen and estradiol secretion by cultured human term trophoblast. J Clin Endocrinol Metab. 57;1311-3, 1983.19. Hochberg Z, Hertz P, Benderly A. Caffein stimulates growth hormone secretion by cultured rat pituitary cells. J Endocrinol Invest 7;59‑60, 1984.20. Hochberg Z, Bick T, Perlman R, Lahav M, Barzilai D. The modulation of placental actogen secretion by calcium: studies with cultured human term trophoblast. Moll Cell Endocrinol 37;359‑62, 1984.21. Davidai G, Kahanah L, Hochberg Z. Glomerulosa failure in congenital unresponsiveness to ACTH. Clin Endocrinol 20;515‑9, 1984.22. Hochberg Z, Moses AM, Richman RA. Parathyroid hormone infusion test in children and adolescence. Mineral Electr Metab 10;113‑6, 1984.23. Kolin A. Kraiem Z, Kahana L, Hochberg Z. Effect of theophylline on urinary excretion of cyclic AMP calium and phosphorus in newborn subjects. Mineral Electr Metab 10;359‑61, 1984.24. Zadik Z, Kahana L, Kaufman H, Benderly A, Hochberg Z. Salt loss in hypertensive form of congenital adrenal hyperplasia (11‑hydroxylase deficiency). J Cln Endocrinol Metab 58;384‑7,1984.25. Chen T, Hirst MA, Cone CM, Hochberg Z, Tietze HV, Feldman D. 1,25 dihydroxyvitamin D resistance, rickets and alopecia: analysis of receptors and bioresponse in cultured fibroblasts from patients and parents. J Clin Endocrinol Metab 59;383‑8, 1984.26. Sujov P, Kellerman L, Zeltzer M, Hochberg Z. Plasma and urine osmolality in full‑term and preterm infants. Acta Paediatr Scand 73;722‑6, 1984.27. Hochberg Z, Benderly A, Zadik Z. Salt loss in congenital adrenal hyperplasia due to 11‑hydroxylase deficiency. Arch Dis Child 59;1092‑4, 1984.28. Hochberg Z, Benderly A, Levy J, Vardi P, Weisman Y, Chen T, Feldman D. 1,25 dihydroxyvitamin D resistance, rickets and alopecia. Amer J Med 77;805‑11, 1984.29. Hochberg Z, Spiendle A, Guttman H, Colin AA. Leucine induced hypoglycemia in a family: the effect of diphenylhydandtoin, oxprenolol and diazoxide. Hormone Res 20;218‑23, 1984.30. Sujov P, Zeltzer M, Hochberg Z. Normal plasma‑urine osmolality relationship in preterm infants on positive pressure mechanical ventilation. Acta Paediatr Scand 74;601‑3, 1985.31. Abend M, Hochberg Z, Berger A, Kraiem Z. How stressful is phototherapy to newborn infants. Israel J Med Sci 21;926‑7, 1985.32. Hochberg Z, Borochowitz Z, Benderly A, Vardi P, Oren S, Spirrer Z, Heiman I Weisman Y. Does 1,25 dihydroxyvitamin D3 participate in the regulation of hormone release from endocrine glands. J Clin Endocrinol Metab 60;57‑61, 1985.33. Hochberg Z, Schachter Y, Benderly A, Leiberman E, Rosler A. Growth and pubertal development in congenital adrenal hyperplasia due to 11‑hydroxylase deficiency. Amer J Dis Child 139;771‑6, 1985.34. Koren R, Ravid A, Liberman UA, Hochberg Z, Weisman Y, Novogrodski A. Defective binding and function of 1,25 dihydroxyvitamin D3 receptors in peripheral mononuclear cells of patients with end‑organ resistance to 1,25(OH)2D3. J Clin Invest 76;2012‑5, 1985.35. Perlman R, Barzilai D, Bick T, Hochberg Z. The effect of inhibitors on insulin regulation of hormone secretion by cultured human trophoblast. Moll Cell Endocrinol 43;77‑82, 1985.36. Lam M, Benderly A, Ziskind G, Hochberg Z. Androgen receptor inhibition does not affect linear growth of rats. J Pediatr Endocrinol 1;217‑20, 1985.37. Hochberg Z, Bick T, Perlman R, Brandes JM, Barzilai D. The dual effect of calcium on aromatization by cultured human trophoblast. J Steroid Biochem 24;1217‑9, 1986.38. Ben‑Haim S, Ish‑Shalom S, Barzilai D, Hochberg Z. Osmotic threshold for vasopressin release in hyperprolactinemic patients. Mineral Electr Metab 12;210‑2, 1986.39. Hochberg Z, Benderly A, Kahana L, Zadik Z. Requirement of mineralocorticoid in congenital adrenal hyperplasia due to 11‑ hydroxylase deficiency. J Clin Endocrinol Metab. 63;36‑40, 1986.40. Laufer D, Benderly A, Hochberg Z. Dental pathology in calcitriol resistant rickets. J Oral Med 42;272‑5. 1987.41. Hochberg Z, Gardos M, Benderly A. Psychosexual outcome of assigned females and males with 46,XX virilizing congenital adrenal hyperplasia. Europ J Pediatr 146:497‑9, 1987.42. Weisman Y, Bab I, Gazit D, Spirer Z, Jaffe M, Hochberg Z. Long term intracaval calcium infusion therapy in end‑organ resistance to 1,25‑dihydroxy vitamin D. Amer J Med 83;984‑90, 1987.43. Hochberg Z, Diamond E, Lischinski S, Zinder O. Prostatic ejaculate in assigned males with 46,XX congenital adrenal hyperplasia. Arch Andrology 19;187‑9, 1987.44. Colin A, Hochberg Z, Kraiem Z. Maintenance theophylline therapy in children: Effect on urinary calcium, phosphorus and cyclic AMP excretion. Acta Paediatr Scan 76;367‑8, 198745. Hochberg Z, Korman S. Oxandrolone therapy in boys of short stature. J Ped Endoc 2;115‑20,198746. Hochberg Z, Perlman R, Bick T. Interrelated calcium ion and cyclic AMP inhibition of placental lactogen secretion by cultured human term trophoblast. Acta Endocrinol 114;68‑73, 1987.47. Nagler A, Merchav S, Fabian I, Tatarsky I, Weisman Y, Hochberg Z. Myeloid progenitors from the bone marrow of patients with vitamin D resistant rickets (type II) fail to respond to 1,25(OH)2D3. Brit J Hematol 67;267‑71, 1987.48. Merchav S, Tatarsky I, Hochberg Z. Enhancement of human granulopoiesis in vitro by biosynthetic insulin like growth factor I/somatomedin C and human growth hormone. J Clin Invest 81;791‑7, 1988.49. Hochberg Z, Bick T, Perlman R. Two pathways of placental lactogen secretion by cultured human trophoblast. Biochem Med Metab Biol 39;111‑6, 1988.50. Perlman R, Halabi C, Bick T, Hochberg Z. The human placenta as a target tissue for glucagon. Biochem Biophys Res Comm 151:1019‑24, 1988.51. Merchav S, Tatarski I, Hochberg Z. Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin‑like gowth factor I. Br J Haematol 70;267‑71, 1988.52. Etzioni A, Pollack S, Hochberg Z. Immune function in growth hormone ‑ deficient children treated with biosynthetic growth hormone. Acta Paediatr Scand 77:169‑70, 1988.53. Brenner B, Seligsohn U, Hochberg Z. Normal response of factor VIII and von Willebrand factor to 1‑deamino‑8d‑arginine vasopressin in nephrogenic diabetes insipidus. J Clin Endocrin Metab 67;191‑3, 1988.54. Eyal A, Ish‑Shalom S, Hoch Z, Hochberg Z. Androgen therapy in hypogonadotropic hypogonadism: time course of erotosexual functions. Arch Androl 20;163‑9, 1988. 55. Roesler A, Weshler N, Leiberman E, Hochberg Z, , Sack J, Chemke J. 11‑B‑Hydroxylase deficiency congenital adrenal hyperplasia: Update of prenatal diagnosis. J Clin Endocrinol Metab 66;830‑8, 1988.56. Tirosh E, Taub Y, Scher A, Jaffe M, Hochberg Z. Short term efficacy of thyroid hormone supplementation for patients with Down's syndrome and low borderline thyroid function. Amer J Mental Retard 93;652‑6, 1989.57. Hochberg Z, Makhoul I. Thyrotropin suppressibility in patients with congenital hypothyroidism. J Pediatr Endocrinol 3;251‑6, 1989.58. Barnea ER, Perlman R, Bick T, Hochberg Z. Effects of human growth hormone upon term placental hormone secretion in vitro. Gynecol Invest 27;133‑6, 1989.59. Lewinson D, Harel Z, Shenzer P, Silbermann M, Hochberg Z. Effect of thyroid hormone and growth hormone on recovery from hypothyroidism of epiphyseal growth plate cartilage and its adjacent bone. Endocrinol 124;937‑45, 1989.60. Malloy PJ, Hochberg Z, Pike JW, Feldman D. Abnormal binding of vitamin D receptors to deoxyribonucleic acid in a kindred with vitamin D‑dependent rickets, type II. J Clin Endocrinol Metab 68;263‑9, 1989. 61. Etzioni A, Hochberg Z, Pollack S, Meshulam T, Zakut V, Tzechoval E, Keisari Y, Aviram I, Spirer Z, Benderly A, Weisman Y. Defective leucocyte fungicidal activity in end‑organ resistance to 1,25‑dihydroxyvitamin D. Pediatr Res 25;276‑9, 1989.62. Maor G, Hochberg Z, Silbermann M. Growth hormone stimulates the growth of mouse neonatal condylar cartilage in vitro. Acta Endocrinol 120;526‑32, 1989.63. Maor G, Hochberg Z, v d Mark K, Heinegard D, Silbermann M. Human growth hormone enhances chondrogenesis and osteogenesis in a tissue culture system of chondroprogenitor cells. Endocrinol 125:1239‑45, 1989.64. Hertz P, Silbemann M, Even L, Hochberg Z. The effects of sex steroids on the response of cultured rat pituicytes to growth hormone releasing hormone and somatostatin. Endocrinol 125;581‑5, 1989.65. Bick T, Youdim MBH, Hochberg Z. Adaptation of liver membrane somatogenic and lactogenic growth hormone (GH) binding to the spontaneous pulsation of GH secretion in the male rat. Endocrinol 125;1711‑7, 1989.66. Bick T, Youdim MBH, Hochberg Z. The dynamics of somatogenic and lactogenic growth hormone binding: internalization to golgi fractions in the male rat. Endocrinol 125;1718‑22, 1989.67. Ritchie HH, Hughes MR, Thompson ET, Malloy PJ, Hochberg Z, Feldman D, Pyke JW, O'Malley BW. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25‑dihydroxyvitamin D3 resistant rickets in three families. Proc Natl Acad Sci (USA) 86;9783‑7, 1989.68. Barnea ER, Perlman R, Fakih H, Bick T, Kol S, Hochberg Z. The role of catecholeamines in estradiol and progesterone secretion by cultured explants and cells of human term placentae. Acta Endocrinol (Copenh) 121;767‑72, 1989.69. Hochberg Z, Bick T, Harel Z. Alterations of human growth hormone binding by rat liver membranes during hypo‑ and hyperthyroidism. Endocrinol 126;325‑9, 1990.70. Hochberg Z, Bick T, Amit T, Barkey RJ, Youdim MBH. Regulation of the GH‑receptor turnover by growth hormone. Acta Paediatr Scand [Suppl] 367;148‑52, 1990.71. Bick T, Amit T, Barkey RJ, Hertz P, Youdim MBH, Hochberg Z. The interrelationship of growth hormone (GH), liver membrane GH receptor, serum GH‑binding protein activity and insulin‑like growth factor‑I (IGF‑I) in the male rat. Endocrinol 126:1914‑20, 1990.72. Amit T, Barkey RJ, Bick T, Hertz P, Youdim MBH, Hochberg Z. Identification of growth hormone binding protein in rat serum. Mol Cell Endocrinol 70:197‑202, 1990.73. Amit T, Barkey RJ, Youdim MBH, Hochberg Z. A new and convenient assay of growth hormone binding protein activity in human serum. J Clin Endocrinol Metab 71:474‑9, 1990.74. Weisman Y, Jaccard N, Legum C, Spirer Z, Yedwab G, Even L, Edelstein S, Kaye AM, Hochberg Z. Prenatal diagnosis of vitamin D dependent rickets type II: response to 1,25‑dihydroxyvitamin D in amniotic fluid cells and fetal tissues. J Clin Endocrinol Metab 71;937‑43, 1990.75. Hochberg Z. Growth hormone and IGF‑I in growth‑plate growth. Curr Med Liter: Growth and Growth Factors. 5;127‑30, 1990.76. Malloy PJ, Hochberg Z, Tiosano D, Hughes MR, Feldman D. The molecular basis of hereditary 1,25‑dihydroxyvitamin D3 resistant rickets in seven related families. J Clin Inv 86:2071-9, 1990. 77. Shehada N, Hazani A, Rudolf MCJ, Peleg I, Benderly A, Hochberg Z. Neurosecretory dysfunction of growth hormone secretion in thalassemia major. Acta Paediatr Scand 79;790‑5, 1990.78. Gozal D, Colin A, Jaffe M, Hochberg Z. Water, electrolyte and endocrine homeostasis in infants with bronchiolitis. Pediatr Res 27;204‑9, 1990.79. Rudolf MCJ, Zadik Z, Linn S, Hochberg Z. Seasonal variation in growth during growth hormone therapy. Amer J Dis Child 145;769-72, 1991.80. Hochberg Z, Even L, Zadik Z. Mineralocorticoids in the mechanism of gynecomastia in adrenal hyperplasia caused by 11B‑hydroxylase deficiency. J Pediatr 118:258-60, 1991.81. Hochberg Z, Amit T, Zadik Z. Twenty‑four‑hour profile of plasma growth hormone‑binding protein. J Clin Endocrinol Metab 72:236‑9, 1991.82. Hochberg Z, Barkey RJ, Even L, Peleg I, Youdim MBH, Amit T. The effect of human growth hormone (GH) therapy on GH binding protein in GH deficient children. Acta Endocrinol (Copenh) 125;23-7, 1991.83. Baruch Y, Amit T, Hertz P, Enat R, Youdim MBH, Hochberg Z. Decreased serum growth hormone‑ binding protein in patients with liver cirrhosis. J Clin Endocrinol Metab 73;777-80, 1991.84. Amit T, Hertz P, Ish-Shalom S, Lotan R, Luboshitzki R, Youdim MBH, Hochberg Z. Effects of hypo- or hyperthyroidism on growth hormone binding protein. Clin Endocrinol 35;159-62, 1991.85. White PC, Dupont J, New MI, Leiberman E, Hochberg Z, Rosler A. A mutation in CYP11B1 (Arg-448 > His) associated with steroid 11ß-hydroxylase deficiency in jews of Moroccan origin. J Clin Invest 87;1664-7, 1991.86. Hochberg Z, Amit T, Youdim MBH. The growth hormone binding protein as a paradigm of the erythropoietin superfamily of receptors. Cell Signaling 3;85-91, 1991.87. Amit T, Barkey RJ, Youdim MBH, Hochberg Z. Effect of human growth hormone (GH)-binding protein on GH binding to rabbit liver membranes. Metabolism 41:732-7, 1992.88. Altman A, Hochberg Z, Silbermann M. Interactions between growth hormone and dexamethasone in skeletal growth and bone structure of the young mouse. Calcif Tissue Int 51:298-304,1992.89. Bick T, Hochberg Z, Amit T, Isaksson OGP, Jansson JO. Roles of pulsatility and continuity of growth hormone (GH) administration in the regulation of hepatic GH-receptors, and circulating GH-binding protein and insulin-like growth factor-I. Endocrinol 131:423-9, 1992.90. Amit T, Barkey RJ, Youdim MBH, Hochberg Z. Modulation of human growth hormone (hGH) binding to somatogenic and lactogenic receptors by monoclonal antibodies to hGH. Cell Sign 4:553-8, 1992.91. Hochberg Z, Hertz P, Maor G, Oiknine J, Aviram M. Growth hormone and insulin like growth factor-I increase macrophage uptake and degradation of low density lipoprotein. Endocrinol 131:430-5, 1992.92. Amit T, Hochberg Z, Waters MJ, Barkey RJ. Growth hormone and prolactin binding proteins in mammalian serum. Endocrinol 131:1793-803, 1992.93. Hochberg Z, Hertz P, Colin V, Ish-Shalom S, Yeshurun D, Youdim MBH, Amit T. The distal axis of growth hormone in nutritional disorders: GH-binding protein, insulin like growth factor-I (IGF-I) AND IGF-I receptors in obesity and anorexia nervosa. Metabolism 41;106-12, 199294. Hochberg Z, Tiosano D, Even L. Calcium therapy in calcitriol resistant rickets. J Pediatr 121:803-8, 1992.95. Amit T, Ish-Shalom S, Glaser B, Youdim MBH, Hochberg Z. Growth hormone binding protein in patients with acromegaly. Hormone Res 37:205-11, 1993.96. Tirosh E, Rod R, Cohen A, Hochberg Z. Congenital adrenal hyperplasia and cerebral lateralization. Pediatr Neurol 9:198-201, 1993.97. Hochberg Z., Leiberman E, Landau H, Koren R, Zadik Z. Age as a determinant of the impact og growth hormone therapy on predicted adult height. Clin Endocrinol 41:331-5, 1994.98. Hochberg Z, Amit T. The clinical significance of growth hormone binding protein. Clin Pediat Endocrinol 2(Suppl 2):15-20, 1993.99. Maor G, Hochberg Z, Silbermann M. Insulin like growth factor-I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles. Acta Endocrinol 128:56-64, 1993100. Lewinson D, Shenzer P, Hochberg Z. Growth hormone involvement in the regulation of tartrate-resistant acid phosphatase-positive cells that are active in cartilage and bone resorption. Calcif Tissue Int 52:216-21, 1993.101. Amit T, Hochberg Z, Barkey R. Influence of Mg2+ on detection of somatogenic and lactogenic components of GH binding protein in mammalian sera. Biochem J 293:345-9, 1993.102. Fishman A, Hertz P, Hochberg Z Ontogenesis of the sexual dimorphism of growth hormone secretion by perifused rat hemi-pituitaries. Neuroendocrinol 57:782-788, 1993.103. Hochberg Z, Phillip M, Youdim MBH, Amit T. Regulation of the growth hormone (GH) receptor and GH-binding protein by GH pulsatility. Metabolism 42:1617-23, 1993.104. Carmeli E, Hochberg Z, Livne A, Lichtentein I, Kestelboim C, Silberman M, Reznick A. Effect of growth hormone on gastrocnemius muscle of aged rats after immobilization: biochemistry and morphology. J Appl Physiol 57:1529-35, 1993.105. Amit T, Hartmann K, Shoshani G, Baruch Y, Youdim MBH, Hochberg Z. The turnover of growth hormone (GH) binding protein and GH-receptor in rabbit and rat. Mol Cell Endocrinol 94:149-54, 1993.106. Baruch Y, Amit T, Hertz P, Enat R, Shoshany G, Youdim MBH, Hochberg Z. Growth hormone-binding protein and insulin-like growth factor I serum levels in partially hepatectomized rats. Hormone Res 40:173-7, 1993. 107. Hochberg Z, Youdim MBH, Amit T. A mathematical model for appraisal of the impact of GH binding protein on GH receptor binding. Growth Regulation 4:8-13, 1994.108. Hochberg Z, Bick T, Amit T. Stoichiometry of the pulsating growth hormone (GH) binding to the GH-binding protein and the turnover GH-receptor. Proc Soc Exp Biol Med 206:249-52, 1994.109. Amit T, Chacham H, Dali O, Hertz P, Barkey R, Hochberg Z. The HepG2 cell line in the study of growth hormone receptor / binding protein. Mol Cell Endocrinol 101:29-36, 1994.110. Lewinson D, Bialik G, Hochberg Z. Differential effects of hypothyroidism on the cartilage and the osteogenic process in the mandibular condyle: recovery by growth hormone and thyroxine. Endocrinol 135:1504-10, 1994.111. Zadik Z, Chalew S, Zung A, Landau H, Leiberman E, Koren R, Voet H, Hochberg Z, Kowarski AA. Effect of long term growth hormone therapy on bone age and pubertal maturation in boys with and without classical growth hormone deficiency. J Pediatr 125:189-95, 1994.112. Hochberg Z, Amit T, Flyvbjerg A, Dorup I. Growth hormone (GH) receptor and GH-binding protein deficiency in growth failure of potassium depleted rats. J Endocrinol 147:253-8, 1995.113. Bick T, Amit T, Mansur M, Bar-Am O, Youdim MBH, Hochberg Z. Regulation of cellular rabbit growth hormone (GH) receptor and GH binding protein generation in vitro. Endocrinology 137:3977-85, 1996.114. Amit T, Bick T, Youdim MBH, Hochberg Z. In search of the cellular site of growth hormone (GH) binding protein cleavage from the rabbit GH receptor. Endocrinology 137:3986-91, 1996.115. Phillip M, Chalew SA, McCarter Jr RJ, Amit T, Kowarski AA, Hochberg Z. The relationship of growth rate, plasma growth hormone (GH) concentration and GH binding protein. Metabolism 45:424-429, 1996.116. Hochberg Z, Chayen R, Reiss N, Falik Z, Makler A, Munichor M, Farkas A, Goldfarb H, Ohana N, Hiort O. Clinical biochemical and genetic findings in a large pedigree of male and female patients with 5-reductase 2 deficiency. J Clin Endocrinol Metab 81:2821-2827, 1996.117. Coyle B, Coffey R, Armour JAL, Gausden E, Hochberg Z, Grossman A, Britton K, Pembrey M, Reardon W, Trembath R. Pendred syndrom (goiter and sensorineural hearing loss) maps to the region containing the non-syndromic deafness gene DFNB4. Nature Gen 12:421,199118. Even L, Weisman Y, Goldray D, Hochberg Z. Selective modulation by vitamin D of the renal response to parathyroid hormone: a study in calcitriol resistant rickets. J Clin Endocrinol Metab 81:2836-2840, 1996.119. Gausden E, Armour JAL, Coyle B, Coffey R, Hochberg Z, Grossman A, Reardon W, Trembath R. Thyroid peroxidase: evidence for disease gene exclusion in Pendred syndrome. Clin Endocrinol 44:441-6, 1996120. Hochberg Z, van Lieburg A, Even, L, Brenner B, van Oost BA, Knoers NVAM. Autosomal recessive nephrogenic diabetes insipidus caused by an aquaporin-2 mutation. J Clin Endocrinol Metab 82:686-689, 1997121. Hochberg Z, Aviram M, Rubin D, Pollack S. Decreased sensitivity to insulin like growth factor-1 in Turner syndrome astudy of monocytes and t-lymphocytes. Europ J Clin Invest 27:543-547, 1997.122. Assy N, Hochberg Z, Amit T, Shen-Orr Z, Enat R, Baruch Y, Growth hormone - stimulated insulin like growth factor (IGF) I and IGF - binding protein-3 in liver cirrhosis. J Hepatol 27:796-802, 1997.123. Amit T, Bergman T, Dastot F, Youdim MBH, Amselem S, Hochberg Z. A membrane - fixed truncated isoform of the human growth hormone receptor. J Clin Endocrinol Metab 82:3813-3817, 1997124. Even L, Bronstein V, Hochberg Z. Bone maturation in girls with Turner’s syndrome. Europ J Endocrinol 138:59-62, 1998125. Lampit M, Nave T, Hochberg Z. Water and sodium retention during short term administration of growth hormone to short normal children. Hormone Res 50:83-88, 1998.126. Lampit M. Lorber A, Vilkas DL, Nave T, Hochberg Z. Growth hormone (GH) dependence and GH withdrawal syndrome in GH treatment of short normal children: evidence from growth and cardiac output. Eurp J Endocrinol 138:401-407, 1998127. Assy N, Hochberg Z, Enat R, Baruch Y. Prognostic value of generation of growth hormone-stimulated insulin-like growth factor I (IGF-1) and its binding protein-3 in patients with compensated and decopensated liver cyrrhosis. Digest Dis Sci 43:1317-1321, 1998128. Baruch Y, Assy N, Amit T, Krivoy N, Strickowski D, Shen-Orr Z, Hochberg Z. Spontaneous pulsatility and pharmacokinetics of growth hormone in liver cirrhotic patients. J Hepatol. 29:559-64, 1998.129. Tiosano D, Gershoni R, Mandel H, Lotan R, ZahranY, Parma J, Vassart G, Pannain S, Weiss RE, Refetoff S, Hochberg Z. The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. Thyroid 9:887-894, 1999.130. Hochberg Z, Zadik Z. Final height in young women with Turner syndrome after growth hormone therapy: An open controlled study. Europ J Endocrinol 141:218-224, 1999131. Amit T, Bar-am O, Dastot F, Youdim MBH , Amselem S, Hochberg Z. The human growth hormone (GH) receptor and its truncated isoform: Sulfhydryl group inactivation in the study of receptor internalization and GH-binding protein generation. Endocrinology 140:266-272, 1999. 136. Zuckerman-Levine N, Tiosano D, Eisenhofer G, Bornstein, Hochberg Z. The importance of adrenocortical glucocorticoids for adrenomedullary and physiological response to stress: a study in isolated glucocorticoid deficiency. J Clin Endocrinol metab 86:5920-2924, 2001.137. Amit T, Hochberg Z, M. Yogev-falach M, Youdim MBH, Barkey RJ. Shedding of growth hormone binding protein is inhibited by hydroxamic acid-based protease inhibitors: Proposed mechanism of activation of growth hormone binding proTein secretase. J Endocrinol 169:397-407, 2001. 147. Vottero A, Kimchi-Sarfaty C, Kratzsch J, Miller G, Lafferty A, Chrousos GP, Hochberg Z. Relative abundance of growth hormone receptor isoforms in rhesus monkey tissues and human transformed lymphocytes. Horm Metab Res 35:1-6, 2003. 148. Vottero A, Kimchi-Sarfaty C, Kratzsch J, Chrousos GP, Hochberg Z. Transcriptional and translational regulation of the splicing isoforms of the growth hormone receptor by glucocorticoids. Horm Metab Res 35:7-12, 2003 149. Friedberg M, Zoumakis E, Hiroi N, Bader T, Chrousos GP, Hochberg Z. Modulation of 11ß -hydroxysteroid dehydrogenase type 1 in mature human subcutaneous. J Clin Endocrinol Metab 88:385-93, 2003 150. Sherbet D, Tiosano D, Kwist KM, Hochberg Z, Auchus RJ. CYP17 mutation E305G causes isolated 17, 20-lyase deficiency by selectively altering substrate binding. J Biol Chem 278:48563-9, 2003 151. Tiulpakov A, Rubtso R, Dedov I, Peterkova V, Bezlepkina O, Chrousos GP, Hochberg Z. A novel C-terminal growth hormone receptor (GHR) mutation results in impaired GHR-Stat5 but normal Stat-3 signaling. J Clin Endocrinol Metab 90:542-7, 2005 152. Fruchter O, Kino T, Zoumakis E, Alesci S De Martino M, Chrousos GP, Hochberg Z. The human glucocorticoid receptor (GR) isoform b differentially suppresses GRa-induced transactivation stimulated by synthetic slucocorticoid. J Clin Endocrinol Metab 90:3505, 2005. 153. Hochberg Z, Khaesh-Goldberg I, Partsch C-J, Zadik Zz, Bistritzer T, Cohen A, Doveh E, Sippell W, Dunkel L. Differences in infantile growth patterns in Turner syndrome girls with and without spontaneous puberty. Horm metab res 37:236-41, 2005 154. Bergman R, Schein-Goldshmid R, Hochberg Z, Ben-Izhak O, Sprecher E. The alopecia associated with vitamin D-dependent rickets type IIA and with hairless gene mutations: A comparative clinical, histological and immunohistochemical study. Arch Dermatol 141:343-351, 2005. 155. Paperna T, Gershoni-Baruch R, Badarneh K, Kasinetz L, Hochberg Z. 2005 Mutations in CYP11B1 and Congenital Adrenal Hyperplasia in Moroccan Jews. J Clin Endocrinol Metab 90:5463-5, 2005. 156. Sulima A, Prisinzano TE, Spande T, Whitaker N, Deschamps JR, Hochberg Z, Jacobson AE, Rice KR. A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone. Steroids 70: 763-769, 2005 157. Lorenz-Depiereux B, Benet-Pages A, Eckstein G, Tenenbaum-Rakover J, Wagenstaller J, Tiosano D, Albers N, Lichtner P, Schnabel D, Hochberg Z, Strom TM. Hereditary Hypophosphatemic Rickets with Hypercalciuria is caused by mutations in the sodium/phosphate cotransporter gene SLC34A3. Amer J Hum Gen 78:193-201,2006 158. Zuckerman–Levin N, Zinder O, Greenberg A, Jacob G, Hochberg Z. Physiological and catecholamine response to sympathetic stimulation in Turner syndrome. Clin Endocrinol 64:410-5, 2006 159. Fruchter O, Zoumakis E, Alesci S, De Martino M, Chrousos G, Hochberg Z. Intracrine modulation of gene expression by intracellular generation of active glucocorticoids. Steroids 71:1001-6, 2006 160. Even L, Bader T, Hochberg Z. Nocturnal calcium, phosphorus and parathyroid pormone in the diagnosis of concealed and subclinical hypoparathyroidism in thalassemia major. Europ J Endocrinol 156:113-116, 2007161. Ben-David S, Zuckerman-Levin N, Epelman M, Shen-Or Z, Levin M, Sujov P, Hochberg Z Parturition itself is the basis for fetal adrenal involution. J Clin Endocrinol Metab 92:93-7, 2007.162. Zuckerman–Levin N, Yaniv I, Schwartz T, Guttmann H, Hochberg Z. Normal DXA bone mineral density but frail cortical bone in Turner syndrome. Clic Endocrinol 67:, 60–64, 2007163. Sagi L, Zuckerman-Levin N, Gawlik A, Ghizzoni L, Buyukgebiz A, Rakover Y, Bistritzer T, Admoni O, Vottero A, Baruch O, Fares F, Malecka-Tendera E, Hochberg Z. Clinical Significance of the Parental Origin of the X chromosome in Turner Syndrome. J Clin Endocrinol Metab 92:846-852, 2007164. Tiosano D, Even L, Shen Orr Z, Hochberg Z. Recombinant hTSH in the diagnosis of congenital hypothyroidism. J Clin Endocrinol Metab 92: 1434-1437, 2007.165. Baroncelli GI, Bereket A, El Kholy M, Audì L, Cesur Y, Ozkan B, Rashad M, Fernández-Cancio M, Weisman Y, Saggese G, Hochberg Z. Rickets in the Middle East: role of environment and genetic predisposition. J Clin Endocrinol Metab 93:1743–1750, 2008.166. Tiosano D, Knopf C, Koren I, Levanon N, Hartmann MF, Hochberg Z, Wudy SA.Metabolic evidence for impaired 17α-hydroxylase activity in a kindred bearing the E305G mutation for isolate 17,20-lyase activity.Eur J Endocrinol. 158:385-392, 2008. 167. Assy N, Pruzansky Y, Gaitini D, Shen Orr Z, Hochberg Z, Baruch Y. Growth hormone-stimulated IGF-1 generation in cirrhosis reflects hepatocellular dysfunction. J Hepatol. 2008 Jul;49(1):34-42.168. German A, Suraiya S, Tenenbaum-Rakover Y, Koren I, Pillar G, Hochberg Z. Control of Childhood congenital adrenal hyperplasia and sleep activity and quality with morning or evening glucocorticoid therapy. J Clin Endocrinol Metab. 93(12):4707-4710, 2008 169. Hellgren G, Andersson B, Nierop AFM, Dahlgren J, Hochberg Z, Albertsson-Wikland KA proteomic approach identified growth hormone dependent nutrition markers in children with idiopathic short stature. Proteome Sci. 2008 Dec 11;6(1):35 170. Makhoul IR, Awad E, TamirA, WeintraubZ, Rotschild A, Bader D, Yurman S, Reich D, Bental B, Jammalieh J, Smolkin T, Sujov P, Hochberg Z. Parental and perinatal factors affecting childhood anthropometry of very-low-birth-weight premature infants: A population-based survey. Acta Paediatr 2009 98, 963–969171. Makhoul IR, Tamir A, Bader D, Rotschild A, Weintraub Z, Yurman S, Reich D, Bental Y, Jammalieh J, Smolkin T, Sujov P, Hochberg Z. In-vitro fertilisation and use of ovulation enhancers may both influence childhood height in very-low-birth-weight infants. Arch Dis Child Fetal Neonatal Ed. 2009 Sep;94(5):F355-9172. Zuckerman–Levin n, Frolova–Bishara T, Militianu D, Levin M, Aharon-Peretz J, Hochberg Z. Androgen Replacement Therapy in Turner Syndrome: A pilot study. J Clin Endocrinol Metab (accepted)
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Clinical Research
Clinical Research1. Hochberg Z. Delayed pubarche in adolescents with adrenal insufficiency. Clin Pediat 19;827‑8, 1980.2. Hochberg Z. Subclinical Hashimoto's thyroiditis in gonadal dysgenesis. Isr J Med Sci 16;847‑8, 1980. 3. Hochberg Z, Lahav M, Shen‑Or Z, Benderly A, Barzilai D. Normal values of urinary free cortisol. Isr J Med Sci 19;286‑8, 1983. 4. Hochberg Z, Gilhar A, Haim S, Friedman R, Levy J, Benderly A. Calcitriol resistant rickets with alopecia. Arch Dermatol 121;646‑47, 1985.5. Gershoni-Baruch R, Goldscher D, Hochberg Z. Ectrodactyly-ectodermal dysplasia-clefting syndrome and hypothalamo-pituitary insufficiency. Amer J Med Gen 68:168-172, 1997.6. Z. Hochberg, L. Even, A. Danon. Amelioration of Polyuria in Nephrogenic DiabetesInsipidus due to Aquaporin-2 Deficiency. Clin Endocrinol 49:39-44, 1998. 8. Leshem E, Bialik V, Hochberg Z. Ultrasonographic assessment of bone maturity in newborns. Horm Res 57:180-186, 2002 9. Kreher NC, Pescovitz OH, Delameter P, Tiulpakov A, Hochberg Z. Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole.. J Pediatr 149:416-420, 2006. 10. Hochberg Z, Tamir A, Zuckerman-Levin N. Parental Origin of the X chromosome in Turner Syndrome. J Clin Endocrinol Metab 92:eletter 13/8/2007
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Books
1. Hochberg Z. Children: Growth and Puberty. Modan‑Tamuz, Tel‑Aviv 1988 2. Hochberg Z (Editor, with 10 coauthors) Practical Algorithms in Pediatric Endocrinology. Karger, Basel 1999. 3. Hochberg Z. Endocrine Control of Bone Maturation. Karger, Basel, 2002 4. Hochberg Z. Children: Growth and Puberty, 1st Book, Indianapolis, IN, 2002 5. Sills R (Editor, with 10 coauthors). Hochberg Z (Series editor). Practical Algorithms in Pediatric Hematology - Oncology. Karger, Basel, 2002. 6. Hochberg Z (Editor, with 13 coauthors) Vitamin D and Rickets. Karger, Basel, 2003 1. Carel J-C, Hochberg Z. (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2005, Karger, Basel, 2005 2. Carel J-C, Hochberg Z. (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2006, Karger, Basel, 2006 3. Carel J-C, Hochberg Z. (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2007, Karger, Basel, 2007 4. Hochberg Z (Editor, with 12 coauthors) Practical Algorithms in Pediatric Endocrinology. 2nd edition. Karger, Basel 20075. Zelikovic I (Editor, with 10 coauthors). Hochberg Z (Series editor) Practical Algorithms in Pediatric Nephrology. Karger, Basel 2008. 6. Carel J-C, Hochberg Z. (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2007, Karger, Basel, 2008
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Book chapters
1. Laron Z, Sarel R, Hochberg Z, Pertzelan A. Puberty in Laron type dwarfism. In: Cacciari E, Prader A (eds), Pathophysiology of puberty. Serono Symp. 36, London, Academic Press, 1980. 2. Feldman D, Chen T, Hirst M, Hochberg Z, Cone C. Vitamin‑D resistant rickets: cultured skin fibroblasts exhibit defective cytoplasmic receptors and unresponsiveness to 1,25(OH)2D3. In: Cohn DV, Potts Jr JT, Fujita T (eds), Endocrine control of bone and calcium metabolism. 75‑77, Elsevier, Amsterdam, 1984. 3. Hochberg Z, Benderly A, Vardi P, Levy J, Shani S. Treatment of children with end‑organ resistance to 1,25‑dihydroxyvitamin D3 by megadose 1‑alpha‑vitamin D3. In: Cohn DV, Potts Jr JT, Fujita T (eds). Endocrine control of bone and calcium metabolism. pp.72‑74, 1984. 4. Weisman Y, Hochberg Z, Pollack S, Meshulam R, Etzioni A. Deceftive neutrophile candidacidal activity in patients with resistance to 1,25(OH)2D3. In: Norman AW, Schaefer K, Grigileit HG, Hervath D (eds). Vitamin D; Chemical biochemical and clinical . pp. 1077‑1078, Walter de Gruyter, Berlin, 1985. 5. Koren DR, Ravid A, Hochberg Z, Weisman Y, Novogrodski A, Lieberman UA. Defective binding and function of 1,25(OH)2D3 receptors in peripheral mononuclear cells of patients with end‑organ resistance to 1,25(OH)2D3. In: Norman AW, Schaefer K (eds), Vitamin D.147‑148, Walter de Gruyter, Berlin 1985. 6. Hochberg Z, Maor G, Lewinson D, Silbermann M. The direct effects of GH on chondrogenesis and osteogenesis. in Heap RB, Lamming GE (Eds) "Biotechnology in Growth Regulation ", Butterworths, London, pp. 123‑128. 1989.7. Hochberg Z, Bick T, T. Amit, Youdim MBH. Regulation of GH receptor-turnover by GH pulasation. In, Melmed S (ed) "Molecular and clinical advances in pituitary disorders". Blackwell, Oxford, 171‑176, 1990 8. Hochberg Z, Weisman Y. Hypophosphatemia in disorders of the perathyroid hormone and vitmain D metabolism. In, Alon U, Chan JCM (Eds) "Phosphate in Pediatric Health and Disease". CRC Press, Ann Arbor, pp. 207-222, 1993. 9. Hochberg Z, Pollack S, Aviram M. Resistance to insulin like growth factor-I in Turner syndrom. in Hibi I, Takano K (Eds) Basic and Clinical Approach to Turner Syndrome. Excerpta Med, Tokyo 233-238, 1993. 10. Weisman Y, Hochberg Z. Vitamin D resistant rickets. in Bardin CW (ed) Current Therapy in Endocrinology, 5th edition, Mosby, St Louis pp 492-5, 1994. 11. Hochberg Z, Rudolf MCG, Shehadeh N, Hazani A. Spontaneous growth hormone (GH) secretion and results of therapy with GH in thalassemic patients. In, S. Ando, C Brancati (Eds) Endocrine Disorders in Thalassemia: Physiological and Therapeutical Aspects. Springer Verlag, Berlin, 1995. 12. Weisman Y, Hochberg Z. Vitamin D resistant rickets. In, Bardin CW (ed) Current Therapy in Endocrinology, 6th edition, Mosby, St Louis, 527-9, 1997 13. Hochberg Z. Rickets past, present and future. In Hochberg Z (Ed) Vitamin D and Rickets. Karger, Basel 2003 14. Hochberg Z, Tiosano D. Disorders of mineral metabolism. In Pescovitz O, Eugster E (Eds) Pediatric Endocrinology: Mechanisms, Manifestations and Management. Philadelphia, Lippincott Williams and Wilkins, pp. 614-640, 2004 15. Hochberg Z, Carel J-C. Editors’ pick: pediatric endocrinology. In Carel J-C, Hochberg Z (Eds) Yearbook of Paediatric Endocrinology. Elsevier, Paris, pp. 201-17, 2004. 16. Carel J-C, Hochberg Z. Editors’ pick: Science and Medicine. In Carel J-C, Hochberg Z (Eds) Yearbook of Paediatric Endocrinology. Elsevier, Paris, pp 185-200, 2004. 1. R Schein-Goldschmid, Z. Hochberg. Vitamin D-Dependent Rickets Type II and Alopecia. In E Sprecher (Ed) Progress in Monogenic Hair Disorders. Nova Biomedical Books, New York, pp 91-8, 2005 2. Tiosano D, Z. Hochberg . Bone and cartilage growth and metabolism. In Kelnar C, Saenger P, Cowell C, Savage M (Eds). Growth Disorders – Pathophysiolofy and Treatment, 2nd edition, Hodder Arnold Ltd, London, 2008 3. Hochberg I, Hochberg Z. Hypothalamic obesity. In Loche S, Maghnie M (eds) Pediatric Neuroendocrinology (in press)
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Books – monographs
1. Hochberg Z. Children: Growth and Puberty. Modan‑Tamuz, Tel‑Aviv 1988 2. Hochberg Z. Endocrine Control of Bone Maturation. Karger, Basel, 2002 3. Hochberg Z. Evolutionary |Perspectives of Child Growth. Submitted manuscript
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Case studies
1. Hochberg Z. Nephrogenic diabetes insipidus in 5 siblings. Harefuah 91;691‑3, 1976.2. Hochberg Z. Hypoglycemic coma in congenital adrenal hyperplasia. Harefuah 99;322‑3, 19803. Korman S, Borochowitz Z, Hochberg Z. Distal renal tubular acidosis with hyperkalemia due to obstructive uropathy. Harefuah 107;62‑4, 1984. 4. Vardi P, Benderly A, Etzioni A, Levi J, Hochberg Z. Hypocalcemia induced by glucocorticoids in a child with hypoparathyroidism treated with 1‑a‑hydroxyvitamin D3. Europ J Pediatr 144;280‑2, 19855. Hochberg Z, Hardof D, Atias D, Spiendle A. Isolated ACTH deficiency with transitory GH deficiency. J Endocrinol Invest 8;67‑70, 19856. Ish‑Shalom S, Ben‑Haim S, Barzilai D, Hochberg Z. Low set osmotic threshold for vasopressin release in a patient with prolactinoma. Hormone Res 23;78‑82, 1986.7. Davidai G, Alon U, Jaffe M, Hochberg Z. Post obstructive urinary concentrating defect: a case study in the role of prostaglandins. Acta Paediatr Scand 76;999‑1002, 19878. Hochberg Z, Etzioni A. Genetic selection in non-classical adrenal hyperplasia. J Clin Endocrinol Metab 80:325-6, 1995. 9. Hochberg Z, Vladowski G, Kerner H. Clinico - pathological conference: Sudden death in Turner's syndrome. Harefuah (hebrew) 129:285-8, 1995.
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Review articles
Review articles: commissioned1. Hochberg Z. Rickets: it’s not just vitamin D deficiency. Curr Opinion Endocrinol Diabetes 8:23-28, 2001 2. Tiosano D, Hochberg Z. Endocrine complications of thalassemia. J Endocrinol Invest 24:716-723, 2001 3. Hochberg Z. Clinical physiology and pathology of the growth plate. Bailliere’s Clin Endocrinol Metab 16:399-419, 2002 4. Hochberg Z. Mechanisms of steroid impairment of growth. Horm Res 58(suppl 1):33-38, 2002 5. Hochberg Z, Bereket A, Davenport M, Delemarre - Van de Waal HA, De Schepper J, Levine MA, Shaw N, Schoenau E, Weisman Y, Zadik Z. Consensus development for the supplementation of vitamin D in childhood and adolescence. Horm Res 58:39-51, 2002 6. Hochberg Z. Extensive personal experience: vitamin D dependent rickets type 2. Horm Res 58:297-302, 2002. 7. Hauner H, Hochberg Z. The Endocrinology of adipose tissue (Editorial). Horm Metab Research 34:605-606, 2002 8. Hochberg Z,, Pacak K, Chrousos GP. Endocrine withdrawal syndromes. Endo Rev 24:523-538, 2003 9. Hochberg Z, Friedberg M, Yaniv L, Bader T, Tiosano D. Hypothalamic regulation of adiposity: the role of 11b-hydroxysteroid dehydrogenase type 1. Horm Metab Res 36:365-9, 2004 10. Hochberg Z. Glucocorticoid withdrawal syndrome. The Endocrinologist 14:152-160, 2004 11. Hochberg Z. Requirements for vitamin D in an indoors culture. Highlights 12:19-24, 2004 12. Rudolf M, Hochberg Z, Speiser P. Perspectives on the development of an international consensus on childhood obesity. Arch Dis Child 90:994-6, 200513. Hochberg Z. Metabolomics of the obese. Int J Obes (Lond). 30:Suppl 2:S4. 200614. Fischer-Posovszky P, Wabitsch M, Hochberg Z. Endocrinology of adipose tissue – an update. Horm Metab Res May;39:314-21, 200715. Hochberg Z. Juvenility in the Context of Life History Theory. Arch Dis Child 93(6):534-9, 200816. Mårild S, Dahlgren J, Hochberg Z. Obesity in children and adolescents – pre-treatment predictors of response to interventional life- style studies: a systematic review. Obesity Metab 5:54-59, 200917. Tiosano D, Hochberg Z. Hypophosphatemia: the common denominator of all rickets. J Bone Mineral Metab 27:392-401, 2009 Review articles: author initiative 18. Hochberg Z, Winter ST. The overweight infant: disatvantages. Harefuah 91;357‑8, 197619. Hochberg Z. Neonatal thyrotoxicosis. Harefuah 94;299‑300, 1978.20. Hochberg Z, Benderly A. Disorders of osmoreceptors for secretion of antidiuretic hormone. Harefuah 102;295‑7, 1982.21. Hochberg Z. Human growth hormone treatment: synthetic or extracts. (letter) Harefuah22. Hochberg Z. Calcitriol resistant rickets. Harefuah 117;163‑5, 198923. Hochberg Z, Aharonof G, Bistritzer Z, Hirsch H, Hanukoglo A. Zadik Z, Theodore R. New indication for growth hormone therapy in patients with growth failure. Harefuah 119, 243‑4, 1990 24. Hochberg Z. Growth Hormone therapy: the ethical angle. Acta Paediat Scan [Supp] 367;1‑3,1990.25. Rosenfeld R, Hochberg Z, Albertsson‑Wikland K et al. A consensus statement on growth hormone therapy. Acta Paediatr Scand [Suppl] 367;177‑8, 1990.26. Rudolf MCJ, Hochberg Z. Are boys more vulnerable to psychological growth retardation? Develop Med Child Neurol 32;1022‑5, 1990.27. Hochberg Z, Aharonof G, Bistritzer Z, Hirsch H, Hanukoglo A. Zadik Z, Theodore R. New indication for growth hormone therapy in patients with growth failure. Harefuah 119, 243‑4, 199028. Fishman A, Hochberg Z, Growth hormone therapy for Turner's syndrome. Harefua 121:281-5, 1991.29. Hochberg Z. Clinical and pharmacological aspects of growth hormone therapy (Editorial). Harefuah 126:552-6, 199430. Hochberg Z, Weisman Y. Calcitriol resistant rickets due to vitamin D receptor defects. Trends Endocrinol Metab 6:216-220, 199531. Hochberg Z. Growth hormone in search of a stature (editorial). Harefuah 136:39-40, 1999.32. Juul A, Bernasconi S, Chatelain P, Hindmarsh P, Hochberg Z, Hokken-Koelega H, de Munick Kaizer-Scharma SMPF, Kiess W, Oberfield S, Parks J, Strasburger CJ, Volta C, Westphal O, Skakkebaek NE. Diagnosis of growth hormone (GH) deficiency and the use of GH in children with growth disorders. Hormone Res 51:284-299, 1999.33. Amit T, Youdim MBH, Hochberg Z. Clinical Review: Does serum growth hormone (GH) binding protein reflect human GH receptor function? J Clin Endocrinol Metab 85:927-932, 2000 35. Hartman C, Hochberg Z, Shamir R. Osteoporosis in pediatrics. Isr Med Assoc J. 5:509-515, 2003 36. Schoenau E, Saggese G, Peter F, Baroncelli GI, Shaw NJ, Crabtreed NJ, Zadik Z, Neu CM, Noordamf C, Radettig G, Hochbergh Z. From bone biology to bone analysis. Horm Res 61:257-69, 2004 37. Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z. Consensus development: Childhood obesity. J Clin Endocrinol Metab 90:1871-1887, 2005 38. Iughetti L, Shalitin S, de Simone M, Dahlgren J, Predieri B, Chalew S, Hochberg Z Definition and epidemiology of obesity in children and adolescent. J Endocrinol Invest 29 (Suppl 5): 34-41, 2006.39. Hochberg Z, Albertsson-Wikland K. Evo devo of child growth. Pediatr Res 64:2-7, 200840. Hochberg Z. Evo-Devo of child growth II: human life history and transition between its phases. Eur J Endocrinol. 160:135-141, 2009 41. Latzer Y, Edmunds L, Fenig S, Golan M, Gur E, Hochberg Z, Levin-Zamir D, Zubery E, Speiser PW, Stein D. Managing childhood overweight: behavior, family, pharmacology and bariatric surgery interventions. Obesity (Silver Spring). 17:411-23, 2009
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